fa روش های تشخیص مایکوباکتریوم های پاتوژن انسانی - با نگرش مولکولی عمومى General مروری Review <div style="text-align: justify;"><span style="font-size:12.5pt"><span style="line-height:17pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span b="" mitra="" style="font-family:"><span style="color:black"><span class="latin" new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:10.0pt">زمینه</span></b></span><span class="latin" new="" roman="" style="font-family:" times=""><b><span dir="LTR" style="font-size:10.0pt">: </span></b></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">جنس</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مایکوباکتریوم</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">شامل</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیش</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">از</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra"> 160 </span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">گونه</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">است،که</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">برخی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">از</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">آنها</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">برای</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">انسان</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیماریزا</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">هستند</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra">. </span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">انواع</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیماری</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ها،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">از</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">جمله</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیماری</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ریوی،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">عفونت</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">پوست</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">و</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بافت</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">نرم،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">لنفادنیت</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">و</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیماری</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">منتشره،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">توسط</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مایکوباکتریوم</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ها</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ایجاد</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">می</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span calibri="" style="font-family:">‌</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">شوند</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra">. </span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">تشخیص</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">دقیق</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">گونه</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ها</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">در</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">درمان</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">صحیح</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیماری</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ناشی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">از</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مایکوباکتریوم</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span calibri="" style="font-family:">‌</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ها</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">از</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">اهمیت</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بالایی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">برخوردار</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">است</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra">. </span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">متداول</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ترین</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">روش</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مورد</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">استفاده</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">برای</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">تشخیص</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مایکوباکتریوم</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ها</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">شامل</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">علائم</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بالینی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">و</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">آزمایش</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">نمونه</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ها،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">روش</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">میکروسکوپی،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">سرولوژی،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">رادیولوژی،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">آزمون</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیوشیمیایی،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">کشت،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">تکنیک</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">برپایه</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">تقویت</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">اسیدهای</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">نوکلئیک</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:.05pt"> (NAATs)</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">از</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">جمله</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="letter-spacing:.05pt">PCR</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">تکثیر</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">و</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">توالی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">یابی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ژن</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ها</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">و</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">غیره</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">می</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span calibri="" style="font-family:">‌</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">باشد</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra">. </span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">دراین</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مقاله</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مروری،</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">پیشرفت</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span calibri="" style="font-family:">‌</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">اخیر</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">در</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">آزمایش</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span calibri="" style="font-family:">‌</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مولکولی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">برای</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">تشخیص</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">سل</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">و</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">سایر</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بیماری</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">های</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مایکوباکتریایی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">را</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">با</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">در</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">نظر</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">گرفتن</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">حساسیت</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">و</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">ویژگی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">آنها</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">مورد</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">بررسی</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">قرار</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">می</span></span></span> <span class="latin" new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="font-family:Mitra">دهیم</span></span></span><span class="latin" new="" roman="" style="font-family:" times=""><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra">.&nbsp; </span></span></span></span></span></span></span></span></span></div> <div style="text-align: justify;">Background: The genus mycobacterium comprises more than 160 species, some<br> of which are pathogenic to humans. A variety of diseases, including pulmonary disease, skin and soft tissue infections, lymphadenitis, and disseminated disease, are caused by mycobacteria. Accurate detection of species is of great importance in the correct treatment of diseases caused by mycobacteria. The most commonly used methods for the diagnosis of mycobacteria include clinical symptoms and testing samples, microscopic methods, serology, radiology, biochemical tests, culture, nucleic acid amplification techniques (NAATs) including PCR, gene amplification and sequencing, etc. Here, we review recent advances in molecular tests for the detection of tuberculosis and other mycobacterial diseases, considering their sensitivity and specificity.</div> تشخیص, مایکوباکتریوم, روش های مولکولی Detection, Mycobacteria, Molecular methods 121 133 http://jmciri.ir/browse.php?a_code=A-10-1531-5&slc_lang=fa&sid=1 Mehdi Roshdi Maleki مهدی رشدی ملکی me.roshdi@iau.ac.ir 10031947532846007675 10031947532846007675 Yes Assistant professor Department of Microbiology, Malekan Branch دانشگاه آزاد اسلامی ملکان Maryam Ziaei Nafchi مریم ضیائی نافچی 10031947532846007676 10031947532846007676 No Assistant Professor Department of Microbiology, Tehran Medical Branch دانشگاه آزاد تهران