fa آپلازی خالص گلبول‌های های قرمز با عفونت پاروویروس 91B در یک بیمار پیوند کلیه بیماری های کلیه و مجاری ادراری گزارش مورد case report <span style="font-size:11pt"><span style="line-height:17.0pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="AR-SA" style="font-size:15.0pt"><span b="" mitra="" style="font-family:"><span style="color:#16469d">چکیده</span></span></span></b><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:#16469d"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:17.0pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="FA" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">زمینه</span></span></span></span></b><b><span dir="LTR" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">: </span></span></span></span></b><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">عفونت</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پاروویروس</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">B</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">19 </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">یکی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">علل</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مهم</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">آپلازی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">گلبول</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">های</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">قرمز</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra"><span style="color:black"> (</span></span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">Pure</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">red</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">cell</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">aplasia</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra"><span style="color:black">)</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیماران</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پیوند</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کلیه</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تحت</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">درمان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">داروهای</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ایمونوساپرسیو</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">. </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">این</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیماری</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کم</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">خونی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">شدید،</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">رتیکولوسیتوپنی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">یافته</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">های</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">اختصاصی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مغز</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">استخوان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تظاهر</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">می</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کند</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">. </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تشخیص</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بر</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پایه</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مورفولوژی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مغز</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">استخوان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">شناسایی</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">DNA</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ویروس</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">PCR</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">. </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">درمان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ایمونوگلوبولین</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">داخل</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">وریدی</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra"><span style="color:black">(</span></span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">IVIG</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="font-family:Mitra"><span style="color:black">) </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تنظیم</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">داروهای</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ایمونوساپرسیو</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مؤثر</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">اما</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ممکن</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">نیاز</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">به</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تکرار</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">درمان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">به</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">دلیل</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">عود</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">داشته</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">باشد</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">. </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">آگاهی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">این</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">وضعیت</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">برای</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تشخیص</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مدیریت</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">به</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">موقع</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیماران</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پیوندی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کم</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">خونی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مقاوم</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ضروری</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">. </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تاکنون</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">موارد</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مشابهی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">عفونت</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پاروویروس</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">B</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">19 </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیماران</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">به</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">دنبال</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پیوند</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مغز</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">استخوان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تعداد</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کمی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">موارد</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">به</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">دنبال</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پیوند</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کلیه</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">گزارش</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">شده</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">. </span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:17.0pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="FA" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">معرفی</span></span></span></span></b><b> </b><b><span lang="FA" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">مورد</span></span></span></span></b><b><span dir="LTR" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">: </span></span></span></span></b><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">این</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مقاله</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">هدف</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ما</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">معرفی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">یک</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیمار</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مبتلا</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">به</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">عفونت</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پاروویروس</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">B</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">19 </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بعد</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ازچهار</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ماه</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پیوند</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کلیه</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیمارستان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">هاشمی</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">نژاد</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تهران</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">که</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">تشخیص</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">درمان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">مناسب</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بهبود</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پیدا</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کرد</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">.</span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:17.0pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:Calibri,sans-serif"><b><span lang="FA" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">نتیجه</span></span></span></span></b><b> </b><b><span lang="FA" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">گیری</span></span></span></span></b><b><span dir="LTR" style="font-size:12.5pt"><span b="" mitra="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">:</span></span></span></span></b> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">PRCA</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیماری</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ناشایعی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ولی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کم</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">خونی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پایدار</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ایزوله</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بزرگسالان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">دارای</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">نقص</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ایمنی،</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">همراه</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">رتیکولوسیتوپنی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بدون</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">شواهد</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">اتیولوژیک</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">دیگر</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">برای</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کم</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">خونی،</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">باید</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">آپلازی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">خالص</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">گلبول</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">های</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">قرمز</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ناشی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">پاروویروس</span></span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">B</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">19 </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">را</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">رد</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کرد</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">. </span></span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">قدم</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">اصلی</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">درمان</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">این</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">بیماران</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">کاهش</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">درمان</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="color:black">‌</span></span><span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">های</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">ایمونوساپرسیو</span></span></span> <span lang="FA" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">است</span></span></span><span dir="LTR" style="font-size:12.5pt"><span style="font-family:Mitra"><span style="color:black">.&nbsp; </span></span></span></span></span></span></span></span></span></span> <span style="font-size:11pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="line-height:107%"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:14.0pt"><span style="font-family:IRMitra"><span style="color:#16469d"><span style="letter-spacing:-.05pt">Abstract</span></span></span></span></b><b><span style="font-size:12.0pt"><span style="font-family:IRMitra"><span style="color:black"><span style="letter-spacing:-.05pt"></span></span></span></span></b></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:13.0pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:12.0pt"><span style="font-family:IRMitra"><span style="color:black"><span style="letter-spacing:-.05pt">Background: </span></span></span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"><span style="letter-spacing:-.05pt">Parvovirus B19 infection is one of the important causes of pure red cell aplasia (PRCA) in kidney transplant patients undergoing immunosuppressive therapy. This condition manifests with severe anemia, reticulocytopenia, and specific bone marrow findings. Diagnosis is based on bone marrow morphology and detection of viral DNA by PCR. Treatment with intravenous immunoglobulin (IVIG) and adjustment of immunosuppressive drugs is effective, but repeated treatment may be necessary due to relapse. Awareness of this condition is essential for timely diagnosis and management of transplant patients with refractory anemia. So far, similar cases of parvovirus B19 infection have been reported in patients following bone marrow transplantation and a few cases following kidney transplantation.</span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:13.0pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:12.0pt"><span style="font-family:IRMitra"><span style="color:black"><span style="letter-spacing:-.05pt">Case Presentation: </span></span></span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"><span style="letter-spacing:-.05pt">In this article, our aim is to introduce a patient with parvovirus B19 infection four months after kidney transplantation at Hasheminejad Kidney Center in Tehran, who improved with appropriate diagnosis and treatment.</span></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:13.0pt"><span style="text-autospace:none"><span style="vertical-align:middle"><span style="font-family:Calibri,sans-serif"><b><span style="font-size:12.0pt"><span style="font-family:IRMitra"><span style="color:black"><span style="letter-spacing:-.05pt">Conclusion:</span></span></span></span></b><b> </b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"><span style="letter-spacing:-.05pt">PRCA is a rare disease, but in adults with isolated persistent anemia who have immunodeficiency, accompanied by reticulocytopenia and no other etiologic evidence for anemia, pure red cell aplasia caused by parvovirus B19 should be ruled out. The main step in treatment for these patients is reducing immunosuppressive therapy.</span></span></span></span></span></span></span></span></span> آپلازی خالص گلبول‌های‌های قرمز (PRCA), عفونت پاروویروس B19, پیوند کلیه Pure red cell aplasia, Pavovirus B19, Renal transplant 69 74 http://jmciri.ir/browse.php?a_code=A-10-1789-1&slc_lang=fa&sid=1 Bahareh Marghoob بهاره مرغوب baharehmarghoob@yahoo.com 2219119475 10031947532846009520 Yes of Nephrology, Department of Nephrology, Hasheminejad Kidney center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran گروه نفرولوژی، دانشکده پزشکی، بیمارستان فوق تخصصی شهید هاشمی نژاد، دانشگاه علوم پزشکی ایران، تهران، ایران Banafshe Dormanesh بنفشه درمنش dr.dormanesh@yahoo.com 10031947532846009521 10031947532846009521 No of Pediatric Nephrology, Department of Pediatric, AJA University of Medical Sciences, Tehran, Iran فوق تخصص بیماریهای کلیه در کودکان، گروه کودکان، دانشگاه علوم پزشکی ارتش، تهران، ایران