Journal of Medical Council of Iran
Volume 43 - Series of Sessions on Post-Acute COVID-19 Syndrome
jmciri 2025, 43 - Series of Sessions on Post-Acute COVID-19 Syndrome: 26-36 |
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Assadiasl S, Faezi S T, Soleimanifar N, Zolfaghari M, Rostamian A, Esteghamati A et al . Autoimmune and Rheumatologic Disorders in Post-COVID Syndrome. jmciri 2025; 43 (S1) :26-36
URL: http://jmciri.ir/article-1-3449-en.html
URL: http://jmciri.ir/article-1-3449-en.html
Sara Assadiasl 
, Seyedeh Tahereh Faezi , Narjes Soleimanifar , Mohammadali Zolfaghari , Abdolrahman Rostamian , Alireza Esteghamati , Mohammad Hossein Niknam
, Seyedeh Tahereh Faezi , Narjes Soleimanifar , Mohammadali Zolfaghari , Abdolrahman Rostamian , Alireza Esteghamati , Mohammad Hossein Niknam
Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Abstract: (149 Views)
Background: Post-coronavirus syndrome has posed challenges on various specialties in recent years due to its diagnostic and therapeutic complexities. This article summarizes the findings related to the pathogenesis of autoimmune disease after COVID-19 infection in patients, and then presents its rheumatologic symptoms and complications in patients with general and specific symptoms.
Results: A variety of general and tissue-specific autoantibodies i produced during COVID-19 infection and cause various symptoms in target organs. The most significant antibodies include antinuclear antibodies, antiphospholipid antibodies, and anti-ACE2 antibodies. COVID-19 infection has also caused a significant increase in the incidence of some rheumatologic diseases such as rheumatoid arthritis. New-inset vasculitis with severe and unusual clinical manifestations, as well as an increase in fibromyalgia cases, are also common observations after contracting COVID-19. The similarity between the general symptoms of post-corona syndrome, such as fatigue and muscle and joint pain, and the symptoms of rheumatologic diseases, makes it difficult to distinguish this condition from new cases of the disease.
Conclusion: Paying attention to persistent or new symptoms in patients who have recovered from COVID-19 infection and differentiating them from symptoms of rheumatologic and autoimmune diseases is helpful in managing post-coronavirus syndrome
Results: A variety of general and tissue-specific autoantibodies i produced during COVID-19 infection and cause various symptoms in target organs. The most significant antibodies include antinuclear antibodies, antiphospholipid antibodies, and anti-ACE2 antibodies. COVID-19 infection has also caused a significant increase in the incidence of some rheumatologic diseases such as rheumatoid arthritis. New-inset vasculitis with severe and unusual clinical manifestations, as well as an increase in fibromyalgia cases, are also common observations after contracting COVID-19. The similarity between the general symptoms of post-corona syndrome, such as fatigue and muscle and joint pain, and the symptoms of rheumatologic diseases, makes it difficult to distinguish this condition from new cases of the disease.
Conclusion: Paying attention to persistent or new symptoms in patients who have recovered from COVID-19 infection and differentiating them from symptoms of rheumatologic and autoimmune diseases is helpful in managing post-coronavirus syndrome
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