Journal of Medical Council of Iran
مجله علمی پژوهشی سازمان نظام پزشکی
Volume 42, Issue 4 (2025)
jmciri 2025, 42(4): 72-74 |
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Dormanesh B. All about the Rotavirus Vaccination. jmciri 2025; 42 (4) :72-74
URL: http://jmciri.ir/article-1-3353-en.html
URL: http://jmciri.ir/article-1-3353-en.html
Pediatric Department, AJA University of Medical Sciences, Tehran, Iran
Abstract: (41 Views)
Abstract
Rotavirus, a double-stranded RNA virus from the Reoviridae family, is the most common viral cause of severe acute diarrhea in children and infants in countries that have not been vaccinated against it, with more than 25 million outpatient visits, 2 million hospitalizations and it accounts for about 440,000 deaths of children under 5 years old. At present, more than 120 countries of the world have included vaccination against rotavirus in their health guidelines. Rotavirus has two proteins G and P, which are found in more than 90% of human infections with 5 types of GP connections (G1P, G2P, G3P, G4P, G9P). Rotasiil oral vaccine manufactured by the Serum Institute of India, and this pentavalent vaccine derived from these 5 common strains of the world is prepared from human and bovine strains. In Iran, Rotasiil oral vaccine has been integrated into the national vaccination program since December 2024 and is administered free of charge for all infants in three doses at the age of 2, 4 and 6 months, except for two cases of severe immunodeficiency and digestive abnormalities prone to intestinal twisting. No serious and dangerous complications have been reported for it.
Rotavirus, a double-stranded RNA virus from the Reoviridae family, is the most common viral cause of severe acute diarrhea in children and infants in countries that have not been vaccinated against it, with more than 25 million outpatient visits, 2 million hospitalizations and it accounts for about 440,000 deaths of children under 5 years old. At present, more than 120 countries of the world have included vaccination against rotavirus in their health guidelines. Rotavirus has two proteins G and P, which are found in more than 90% of human infections with 5 types of GP connections (G1P, G2P, G3P, G4P, G9P). Rotasiil oral vaccine manufactured by the Serum Institute of India, and this pentavalent vaccine derived from these 5 common strains of the world is prepared from human and bovine strains. In Iran, Rotasiil oral vaccine has been integrated into the national vaccination program since December 2024 and is administered free of charge for all infants in three doses at the age of 2, 4 and 6 months, except for two cases of severe immunodeficiency and digestive abnormalities prone to intestinal twisting. No serious and dangerous complications have been reported for it.
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